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GlutathioneVET 60 caps by Thorne Research
GlutathioneVET 60 caps by Thorne Research


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Reduced glutathione (GSH) occurs naturally in all animal cells; however, the liver is the largest reservoir in the body. GSH is a cofactor for dozens of enzymes involved in detoxification and is essential for phase I and phase II liver detoxification. Unfortunately, conditions that negatively affect liver health usually result in decreased concentrations of liver glutathione; for example, glutathione levels are reduced in cats with hepatic lipidosis.

As a potent endogenous antioxidant, GSH directly quenches several reactive oxygen species. Animal structures and functions that can benefit from maintaining normal levels of glutathione are numerous and include hepatic, pulmonary, immune system, bowel, carbohydrate metabolism, cardiovascular, cognitive, and eye health.

Maintaining optimal levels of glutathione appears to be important for supporting cognitive function, especially as pets age. The normal process of aging is associated with a decrease in glutathione regulation, which can result in increased oxidative activity. Less than optimum levels of glutathione are observed in animals experiencing a decline in cognitive function. In humans, those living over 100 years tend to have higher glutathione reductase activity – thus, higher glutathione levels.

A common mistaken belief is that glutathione is not well absorbed when taken orally, but significant data confirms it is efficiently absorbed across the intestinal epithelium by a specific uptake system. In the case of GlutationeVET, Thorne Vet has gone a step further to assure efficient absorption. Absorption of oral glutathione can be affected by stomach acid or enzymes in the duodenum, which can break glutathione into its amino acid components. However, the sustained-release properties of GlutathioneVET protect it from stomach acid and digestive enzymes, allowing slower release and a more steady blood level of this essential compound.

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