A revolutionary enzyme product from Kirkman® The human intestinal tract contains seven enzymes that split dietary disaccharides into free monosaccharides. Until now, commercially available enzyme products contained enzyme ingredients that had the activity of only some of these disaccharidase enzymes. One in particular, however, sucrase-isomaltase complex, was only partially represented in these products. Invertase is present in these products to hydrolyze sucrose to yield glucose and fructose, and to hydrolyze other complex sugars that contain fructose, so it acts as a sucrase enzyme. The isomaltase fraction of that human enzyme is not represented because there is no commercially available form of isomaltase in the world. The importance of this missing enzyme fraction was confirmed in January 2004 by R. Kushak, Ph.D., and T. Buie, M.D., of Massachusetts General Childrens Hospital in an intestinal biopsy study involving 100 children with special requirements and sensitivities. The study showed that 60% of these patients had weak lactase activity and 25-45% had weak isomaltase/palatinase activity, which substantiated their special dietary need for an enzyme providing isomaltase/palatinase activity. This study provided the impetus for Kirkman® to search for an enzyme that had isomaltase/palatinase activity. Kirkman® found that enzyme and trademarked it Isogest®. Isogest® has the ability to split isomaltose into two molecules of glucose and to split palatinose into one molecule of glucose and one molecule of fructose. The result of including this new enzyme is better, more complete carbohydrate digestion. Currently, no other enzyme product can offer this added activity. EnZym-Complete/DPP-IV II with Isogest® is Kirkmans second generation version of Enzym-Complete/DPPIV. It contains all the enzymes present in Enzym-Complete/DPPIV plus Isogest®. The presence of Isogest® gives this product the equivalent activity of the isomaltase fraction of the sucrase/isomaltase enzyme found in the human digestive system. Individuals currently using Enzym-Complete/DPPIV who are getting partial results and still need some improvement or individuals using other enzymes who are not completely satisfied with the results should try EnZym-Complete/DPP-IV II with Isogest® formula. Physicians and parents who evaluated products containing Kirkmans Isogest® reported the following: less bloating more regular bowel habits less constipation more normal stools better overall digestion with less discomfort firmer stools less gas less diarrhea less sensitivity to dairy and grains less odorous bowel movements No adverse effects were reported. FREE OF: Sugar, soy, wheat, casein, gluten, milk, preservatives, yeast, gelatin, flavorings or colorings.Supplement FactsServing Size: 2 capsulesServings per Container: 45Each Serving ContainsAmount Per Serving% Daily Value*DPP-IV (activity)50,000 HUT*Protease (from Vegetable Pancreatin 4X/NF)38,000 DAPU*Alkaline Protease 50 DAPU*FP 31 Protease100 HU*AFP (acid fast protease)100 SAPU*Bromelain (pineapple source/1,280,000 FCCPU) 100 BTU*Papain (sulfite-free papaya source)2,000,000 FCCPU*Amylase (from Vegetable Pancreatin 4X/NF)89,000 MWU*Alpha Amylase100 SKBU*Glucoamylase30 AGU*Alpha-Galactosidase50 Gal U*Lactase1000 LAU*Maltase200 MWU*Invertase (Sucrase)400 SU*Cellulase200 CU*Xylanase (emicellulase)100 XU*Phytase10 PU*Lipase (from vegetable pancreatin 4X/NF)15,000 LU*Isogest100 mg** Daily Value not establishedOther Ingredients: Plant and vegetable cellulose, and silica.Does Not Contain: Wheat, gluten, milk, casein, corn, soy, yeast, sugar, egg, rice bran, artificial sweeteners, colorings or flavorings, stearates, preservatives, and salicylates. Designed exclusively for the sensitive individual.